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Acetyl-CoA Acetyltransferase 1 (ACAT1) (C-Term) Peptide

Name

Acetyl-CoA Acetyltransferase 1 (ACAT1)
Synonyms
T2, MAT, ACAT, THIL, SOAT, STAT, ACACT, ACAT1, RP11-215I23.2, ald, Acact, ACAT-1, AW550831, 8430426K15Rik, RATACAL, Acat-1, Acat, 6330585C21Rik, fd16h07, fd20g06, zgc:86832, wu:fd16h07, wu:fd20g06, MG ... show more
Binding Site

C-Term
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN697224
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Immunogen Synthetic peptide
Characteristics Blocking peptide for ACAT1 (C-term) antibody ABIN391807
Specificity The synthetic peptide sequence used to generate the antibody AP7560b was selected from the C-term region of human ACAT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Comments

Background: ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in the gene encoding ACAT1 are associated with the alpha-methylacetoaceticaciduria disorder,an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
Synonyms T2, MAT, ACAT, THIL, SOAT, STAT, ACACT, ACAT1, RP11-215I23.2, ald, Acact, ACAT-1, AW550831, 8430426K15Rik, RATACAL, Acat-1, Acat, 6330585C21Rik, fd16h07, fd20g06, zgc:86832, wu:fd16h07, wu:fd20g06, MGC137917, MGC107795, acat1, CEH, TGH, CES2, HMSE, SES1, HMSE1, PCE-1, MGC117365, Es2, MGC109055, LOC100009551

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Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications
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Product Haapalainen, Meriläinen, Pirilä et al.: "Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function." in: Biochemistry, Vol. 46, Issue 14, pp. 4305-21, 2007 (PubMed).

Guo, Chang, Chang: "Functionality of the seventh and eighth transmembrane domains of acyl-coenzyme A:cholesterol acyltransferase 1." in: Biochemistry, Vol. 46, Issue 35, pp. 10063-71, 2007 (PubMed).

Alternatives
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Alternatives for antigen "Acetyl-CoA Acetyltransferase 1 (ACAT1)", type "Peptides"
Reactivities Human (1)