Aurora Kinase A (AURKA) (N-Term) Peptide

Details for Product No. ABIN697732, Supplier: Log in to see
Protein Name
  • 87A7-9/2
  • Aur-A
  • AurA
  • CG3068
  • Dmel\\CG3068
  • aur-A
  • aurA
  • ck10
  • ck[10]
  • l(3)87Ac
  • l(3)ck10
  • Aurora-A
  • Eg2
  • aik
  • ark1
  • aur-a
  • aura
  • aurora2
  • btak
  • pEg2
  • stk15
  • stk6
  • stk7
  • wu:fb37c10
  • wu:fc02c02
  • zgc:100912
  • AURKA
  • aurka
  • AIK
  • ARK1
  • AURA
  • AURORA2
  • BTAK
  • PPP1R47
  • STK15
  • STK6
  • STK7
  • AIRK1
  • AU019385
  • AW539821
  • Ark1
  • Ayk1
  • IAK
  • IAK1
  • Stk6
  • ARK-1
  • aurka-a
  • aurora
  • aurora kinase A
  • hypothetical protein
  • aur
  • aurka
  • Aurora-A
  • AURKA
  • Aurka
Protein Region
N-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP7900a was selected from the N-term region of human AIK . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background Aurora A (AIK) plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Kimura, Kotani, Hattori, Sumi, Yoshioka, Todokoro, Okano: "Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1." in: The Journal of biological chemistry, Vol. 272, Issue 21, pp. 13766-71, 1997 (PubMed).