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Lymphotoxin-alpha (LTA) (Center) Peptide

Details for Product No. ABIN698158, Supplier: Log in to see
Protein Name
  • LT
  • LT-[a]
  • LT-alpha
  • LT[a]
  • LTalpha
  • Ltx
  • TNF-beta
  • TNFSF1
  • Tnfb
  • Tnfsf1b
  • hlb382
  • TNFB
Protein Region
Center
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
Supplier
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Specificity The synthetic peptide sequence used to generate the antibody AP8509c was selected from the Center region of human LTA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background LTA, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Buonaguro, Barillari, Chang et al.: "Effects of the human immunodeficiency virus type 1 Tat protein on the expression of inflammatory cytokines." in: Journal of virology, Vol. 66, Issue 12, pp. 7159-67, 1992 (PubMed).