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Engulfment and Cell Motility 1 (ELMO1) (Center) Peptide

Details for Product No. ABIN698394, Supplier: Log in to see
Protein Name
  • MGC68475
  • ELMO1
  • CED-12
  • CED12
  • ELMO-1
  • 6330578D22Rik
  • C230095H21Rik
  • ELMO1s
  • im:7151147
  • wu:fq24e08
  • zgc:85612
  • engulfment and cell motility 1
  • engulfment and cell motility 1 (ced-12 homolog, C. elegans)
  • ELMO1
  • elmo1
  • Elmo1
Protein Region
Center
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP8761c was selected from the Center region of human ELMO1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background ELMO1 interacts with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes. Similarity to a C. elegans protein suggests that this protein may function in apoptosis and in cell migration.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: "Lysine acetylation targets protein complexes and co-regulates major cellular functions." in: Science (New York, N.Y.), Vol. 325, Issue 5942, pp. 834-40, 2009 (PubMed).