Xeroderma Pigmentosum, Complementation Group A (XPA) (C-Term) Peptide

Details for Product No. ABIN698416, Supplier: Log in to see
Protein Name
  • CG6358
  • DhR14
  • DhXPA
  • DmXPA
  • Dmel\\CG6358
  • Dxpa
  • EG:EG0007.8
  • XPAC
  • Xpa
  • dmXPA
  • dxpa
  • XP1
  • AI573865
  • Xpac
  • xpac
  • xxpa
  • Xeroderma pigmentosum group A-like
  • xeroderma pigmentosum, complementation group A
  • Xpac
  • XPA
  • Xpa
  • xpa
Protein Region
Peptide Type
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP8784b was selected from the C-term region of human XPA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications States, McDuffie, Myrand, McDowell, Cleaver: "Distribution of mutations in the human xeroderma pigmentosum group A gene and their relationships to the functional regions of the DNA damage recognition protein." in: Human mutation, Vol. 12, Issue 2, pp. 103-13, 1998 (PubMed).