Alkaline Ceramidase 3 (ACER3) (C-Term) Peptide

Details for Product No. ABIN698572, Supplier: Log in to see
Protein Name
  • phca
  • PHCA
  • APHC
  • 1110057L18Rik
  • 5430429L08Rik
  • AV015045
  • Phca
  • RGD1561254
  • alkaline ceramidase 3
  • acer3
  • ACER3
  • Acer3
Protein Region
C-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Specificity The synthetic peptide sequence used to generate the antibody AP8953b was selected from the C-term region of human ACER3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Background ACER3 hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Wheeler, Metter, Tanaka, Absher, Higgins, Zahn, Wilhelmy, Davis, Singleton, Myers, Ferrucci, Kim: "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000685, 2009 (PubMed).

Mao, Obeid: "Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate." in: Biochimica et biophysica acta, Vol. 1781, Issue 9, pp. 424-34, 2008 (PubMed).