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Alkaline Ceramidase 3 (ACER3) (C-Term) Peptide

Name

Alkaline Ceramidase 3 (ACER3)

Synonyms APHC, PHCA, FLJ11238, Phca, AV015045, 1110057L18Rik, 5430429L08Rik, phca, RGD1561254, MGC179542
Binding Site

C-Term

2 references available
Certificates ISO 9001:2008
Catalog no. ABIN698572
Quantity 0.1 mg
Price 49.50 $   Plus shipping costs $45.00
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Additional Information

Immunogen Synthetic peptide
Characteristics Blocking peptide for ACER3 (C-term) antibody ABIN652900
Specificity The synthetic peptide sequence used to generate the antibody AP8953b was selected from the C-term region of human ACER3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Comments

Background: ACER3 hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.

Application Details

Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Restrictions For Research Use only

Publications

Product Mao, Obeid: "Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate." in: Biochimica et biophysica acta, Vol. 1781, Issue 9, pp. 424-34, 2008 (PubMed).

Wheeler, Metter, Tanaka et al.: "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000685, 2009 (PubMed).