Aminoadipate-Semialdehyde Dehydrogenase-phosphopantetheinyl Transferase (AASDHPPT) (Center) Peptide

Details for Product No. ABIN698793
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Protein Name
Synonyms AASD-PPT, LYS2, LYS5, CGI-80, 2010309J24Rik, 2810407B07Rik, AASDHPPT, DDBDRAFT_0186752, DDBDRAFT_0304576, DDB_0186752, DDB_0304576
Protein Region
Center
Application
Blocking Peptide (BP)
Pubmed 1 reference available
Catalog no. ABIN698793
Quantity 0.1 mg
Price
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Specificity The synthetic peptide sequence used to generate the antibody AP9193c was selected from the Center region of human AASDHPPT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Alternative Name AASDHPPT
Background AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
Comment

Background: AASDHPPT is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.

Restrictions For Research Use only
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Strickland, Hoeferlin, Oleinik et al.: "Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase." in: The Journal of biological chemistry, Vol. 285, Issue 3, pp. 1627-33, 2010 (PubMed).

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