Adenylate Cyclase 7 (Adcy7) (Center) Peptide

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Protein Name
  • ADCY7
  • ADCY4a
  • ac7
  • AC7
  • AA407758
  • adenylate cyclase 7
  • ADCY7
  • adcy7
  • Adcy7
Protein Region
Center
Application
Blocking Peptide (BP)
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Background ADCY7 encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Townsend, Holliday, Fenyk, Hess, Gray, Hodgson, Cann: "Stimulation of mammalian G-protein-responsive adenylyl cyclases by carbon dioxide." in: The Journal of biological chemistry, Vol. 284, Issue 2, pp. 784-91, 2009 (PubMed).

Jiang, Collins, Davis, Fraser, Sternweis: "Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII." in: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23429-39, 2008 (PubMed).

Hines, Hoffman, Bhave, Saba, Kaiser, Snell, Goncharov, LeGault, Dongier, Grant, Pronko, Martinez, Yoshimura, Tabakoff,: "A sex-specific role of type VII adenylyl cyclase in depression." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 48, pp. 12609-19, 2006 (PubMed).