UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (Center) Peptide

Details for Product No. ABIN699464, Supplier: Log in to see
Protein Name
  • B3Gn-T6
  • BGnT-6
  • beta-1,3-Gn-T6
  • beta3Gn-T6
  • BC039789
  • Core-3
  • Core3
  • UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
  • B3GNT6
  • B3gnt6
Protein Region
Blocking Peptide (BP)
Log in to see
Supplier Product No.
Log in to see

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Lee, Hatakeyama, Yu, Bao, Ohyama, Khoo, Fukuda, Fukuda: "Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex." in: The Journal of biological chemistry, Vol. 284, Issue 25, pp. 17157-69, 2009 (PubMed).

Iwai, Kudo, Kawamoto, Kubota, Togayachi, Hiruma, Okada, Kawamoto, Morozumi, Narimatsu: "Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 12, pp. 4572-7, 2005 (PubMed).

Iwai, Inaba, Naundorf, Zhang, Gotoh, Iwasaki, Kudo, Togayachi, Ishizuka, Nakanishi, Narimatsu: "Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12802-9, 2002 (PubMed).