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UDP-GlcNAc:betaGal beta-1,3-N-Acetylglucosaminyltransferase 6 (Core 3 Synthase) (B3GNT6) (Center) Peptide

Details for Product No. ABIN699464, Supplier: Log in to see
Protein Name
  • B3Gn-T6
  • BC039789
  • beta-1,3-Gn-T6
  • beta3Gn-T6
  • BGnT-6
  • Core-3
  • Core3
Protein Region
Center
Application
Blocking Peptide (BP)
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Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Lee, Hatakeyama, Yu, Bao, Ohyama, Khoo, Fukuda, Fukuda: "Core3 O-glycan synthase suppresses tumor formation and metastasis of prostate carcinoma PC3 and LNCaP cells through down-regulation of alpha2beta1 integrin complex." in: The Journal of biological chemistry, Vol. 284, Issue 25, pp. 17157-69, 2009 (PubMed).

Iwai, Kudo, Kawamoto, Kubota, Togayachi, Hiruma, Okada, Kawamoto, Morozumi, Narimatsu: "Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 12, pp. 4572-7, 2005 (PubMed).

Iwai, Inaba, Naundorf, Zhang, Gotoh, Iwasaki, Kudo, Togayachi, Ishizuka, Nakanishi, Narimatsu: "Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12802-9, 2002 (PubMed).