Adenylate Cyclase Activating Polypeptide 1 (Pituitary) (ADCYAP1) (C-Term) Peptide

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Protein Name
  • adcyap1
  • GRF-PACAP
  • zgc:103760
  • xx:af217251
  • pac1
  • pacapr
  • pacapri
  • pacap
  • ADCYAP1
  • PACAP
  • Pacap
  • grf
  • MEDA-7
  • pERp1
  • RGD1310251
  • 2010001M09Rik
  • AV064572
  • adenylate cyclase activating polypeptide 1a
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
  • adenylate cyclase activating polypeptide 1 (pituitary)
  • adenylate cyclase activating polypeptide 1
  • marginal zone B and B1 cell-specific protein
  • marginal zone B and B1 cell-specific protein 1
  • pituitary adenylate cyclase activating polypeptide
  • adcyap1a
  • adcyap1r1
  • adcyap1
  • ADCYAP1
  • Adcyap1
  • MZB1
  • Mzb1
  • PACAP
Protein Region
C-Term
Source
Synthetic
Peptide Type
Synthetic
Application
Blocking Peptide (BP)
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Background ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Hosoya, Kimura, Ogi, Ohkubo, Miyamoto, Kugoh, Shimizu, Onda, Oshimura, Arimura: "Structure of the human pituitary adenylate cyclase activating polypeptide (PACAP) gene." in: Biochimica et biophysica acta, Vol. 1129, Issue 2, pp. 199-206, 1992 (PubMed).

Ohkubo, Kimura, Ogi, Okazaki, Hosoya, Onda, Miyata, Arimura, Fujino: "Primary structure and characterization of the precursor to human pituitary adenylate cyclase activating polypeptide." in: DNA and cell biology, Vol. 11, Issue 1, pp. 21-30, 1992 (PubMed).

Kimura, Ohkubo, Ogi, Hosoya, Itoh, Onda, Miyata, Jiang, Dahl, Stibbs: "A novel peptide which stimulates adenylate cyclase: molecular cloning and characterization of the ovine and human cDNAs." in: Biochemical and biophysical research communications, Vol. 166, Issue 1, pp. 81-9, 1990 (PubMed).