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CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (C-Term) Peptide
|1 reference available|
|Price||49.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Characteristics||Blocking peptide for CEAPB (C-term) antibody ABIN652248|
|Specificity||The synthetic peptide sequence used to generate the antibody AP6815b was selected from the C-term region of human CEBPB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
Background: CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
|Synonyms||LAP, CRP2, TCF5, IL6DBP, NF-IL6, MGC32080, C/EBP-beta, NF-M, Nfil6, IL-6DBP, C/EBPbeta, Il6dbp, CEBPB, C/EBP beta, lap, crp2, tcf5, il6dbp, nf-il6, MGC107842, c/ebp-beta, xC/EBPbeta, cebpbb, cb380, c/ebpb, fe11e05, wu:fe11e05, LOC100136165|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles|
|Restrictions||For Research Use only|
Buck, Poli, van der Geer et al.: "Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha." in: Molecular cell, Vol. 4, Issue 6, pp. 1087-92, 2000 (PubMed).