CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (C-Term) Peptide

Details for Product No. ABIN700096
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Protein Name
Protein Region
C-Term
Source
Synthetic
Antibody Type Synthetic
Application
Blocking Peptide (BP)
Pubmed 1 reference available
Quantity 0.1 mg
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Immunogen Synthetic peptide
Specificity The synthetic peptide sequence used to generate the antibody AP6815b was selected from the C-term region of human CEBPB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Alternative Name CEBPB
Background CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Restrictions For Research Use only
Storage 4
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Background publications Buck, Poli, van der Geer et al.: "Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP beta is required for hepatocyte proliferation induced by TGF alpha." in: Molecular cell, Vol. 4, Issue 6, pp. 1087-92, 2000 (PubMed).

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Catalog No. ABIN700096
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