Lysosomal Protein Transmembrane 4 beta (LAPTM4B) (N-Term) Peptide
| Name | Lysosomal Protein Transmembrane 4 beta (LAPTM4B) |
| Synonyms | LC27, LAPTM4beta, C330023P13Rik |
| Binding Site |
N-Term |
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1 reference available |
| Certificates | ISO 9001:2008 |
| Catalog no. | ABIN700264 |
| Quantity | 0.1 mg |
| Price | 49.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Immunogen | Synthetic peptide |
| Characteristics | Blocking peptide for LAPTM4B (N-term) antibody ABIN652720 |
| Specificity | The synthetic peptide sequence used to generate the antibody AP8774a was selected from the N-term region of human LAPTM4B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Comments |
Background: LAPTM4B belongs to the LAPTM4/LAPTM5 transporter family. It has an active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma. |
Application Details
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles |
| Restrictions | For Research Use only |
Publications
| Product |
Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).
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Sponsorship
2013 BioMed Central Research Awards
2013 BioMed Central Research Awards
