Interleukin 1, beta (IL1B) (AA 117-269) Peptide

Details for Product No. ABIN934955, Supplier: Log in to see
Protein Name
  • il1-b
  • zgc:111873
  • IL-1beta
  • Il-1b
  • IL1B
  • IL-1
  • IL1-BETA
  • IL1F2
  • IL-1BETA
  • IL1beta
  • IL-1B
  • interleukin 1, beta
  • interleukin 1 beta
  • il1b
  • Il1b
  • IL-1B
  • IL1B
Protein Region
AA 117-269
Origin
Human
6
3
2
1
1
1
Source
Escherichia coli (E. coli)
Peptide Type
Recombinant
Application
SDS-PAGE (SDS)
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Sequence MAPVRSLNCT LRDSQQKSLV MSGPYELKAL HLQGQDMEQQ VVFSMSFVQG EESNDKIPVA LGLKEKNLYL SCVLKDDKPT LQLESVDPKN YPKKKMEKRF VFNKIEINNK LEFESAQFPN WYISTSQAEN MPVFLGGTKG GQDITDFTMQ FVSS
Characteristics Purified recombinant Human IL1 beta protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.
Purity > 95 % pure
Endotoxin Level < 1.0 EU per µg of protein (determined by LAL method)
Background Interleukin-1 (IL-1) has been considered a potentially important inflammatory mediator. It is composed of two distinct proteins, called as IL-1 alpha and IL-1 beta. IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta bind to the same receptor and they are structurally related polypeptides that share approximately 20 % amino acid. Recombinant human IL-1 beta was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names: IL beta 1 protein, IL1-beta protein, IL1B protein, Interleukin 1b protein, IL beta 1, IL-1B, Interleukin 1beta protein, IL1F2 protein, beta proprotein protein, IL-1 protein, IL beta-1, IL1 beta, interleukin 1 beta protein, Interleukin 1 protein, IL beta-1 protein
Molecular Weight 17 kDa (154 AA)
Research Area Cardiovascular, Atherosclerosis, Innate Immunity, Cytokines, Growth Factors
Application Notes IL1 beta protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Supplied as a liquid in PBS, pH 7.4.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage RT/-20 °C
Storage Comment Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.
Supplier Images
SDS-PAGE (SDS) image for Interleukin 1, beta (IL1B) (AA 117-269) Peptide (ABIN934955) Figure annotation denotes ug of protein loaded and % gel used.
Product cited in: Charoenphol, Huang, Eniola-Adefeso: "Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers." in: Biomaterials, Vol. 31, Issue 6, pp. 1392-402, 2010 (PubMed).