Matrix Gla Protein (MGP) (AA 20-96) peptide (His tag)

Details for Product No. ABIN935117, Supplier: Log in to see
Protein Name
  • mgp-A
  • MGP
  • LOC100136434
  • mgp
  • MGLAP
  • NTI
  • Mglap
  • matrix Gla protein
  • Matrix Gla protein
  • matrix Gla protein-like
  • mgp-A
  • mgp
  • MGP
  • LOC100136171
  • LOC100136434
  • Mgp
  • LOC100856382
Protein Region
AA 20-96
Origin
Human
2
1
Source
Escherichia coli (E. coli)
Peptide Type
Recombinant
Purification tag / Conjugate
His tag
Application
SDS-PAGE (SDS)
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Sequence MGSSHHHHHH SSGLVPRGSH MYESHESMES YELNPFINRR NANTFISPQQ RWRAKVQERI RERSKPVHEL NREACDDYRL CERYAMVYGYNAAYNRYF
Characteristics Recombinant human MGP protein
Expression System: E.coli
Purity > 90 % pure
Background MGP, also known as Matrix Gla protein, is a protein involved in regulating calcification in the extracellular matrix, in particular in cartilage and arteries. MGP is a vitamin K-dependent protein, and contains five to six residues of Gla, a Ca2+ binding AA requiring vitamin K-dependent gamma carboxylase for its formation. It is found in human bone extracts, likely formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity. Recombinant human MGP protein, fused to His-tag at N-terminus, was expressed in E. coli and denatured using detergent during a conventional chromatography purification process.
Alternative Names: GIG36 protein, NTI protein, MGLAP protein, Matrix Gla protein isoform 2 precursor protein
Molecular Weight 11.8 kDa (98 AA)
Research Area Signaling, Extracellular Matrix, Cell Biology
Application Notes MGP protein has been used in SDS PAGE, and may be suitable for use in other assays
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Liquid. 20 mM Tris-HCl buffer (pH8.0) containing 10 % glycerol.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage RT/-20 °C
Storage Comment Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.
Supplier Images
SDS-PAGE (SDS) image for Matrix Gla Protein (MGP) (AA 20-96) peptide (His tag) (ABIN935117) Figure annotation denotes ug of protein loaded and % gel used.