Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 72-199) Peptide
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- Target See all TNFSF18 products
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- Peptide Type
- Recombinant
- Protein Region
- AA 72-199
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Sequence
- MQLETAKEPC MAKFGPLPSK WQMASSEPPC VNKVSDWKLE ILQNGLYLIY GQVAPNANYN DVAPFEVRLY KNKDMIQTLT NKSKIQNVGG TYELHVGDTI DLIFNSEHQV LKNNTYWGII LLANPQFIS
- Characteristics
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Recombinant human TNFSF18 protein
Expression System: E.coli - Purity
- > 90 % pure
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- Application Notes
- TNFSF18 protein has been used in SDS-PAGE, and may be suitable for use in other applications
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 10 mM sodium citrate (pH 3.5), 10 % glycerol, 0 mMDTT.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
- Can be stored at 4 °C short term (1-2 weeks). For long term storage, aliquot and store at -20 °C or -70 °C.
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- Target
- TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
- Synonyms
- Gitrl Peptide, AITRL Peptide, GITRL Peptide, TL6 Peptide, hGITRL Peptide, TNLG2A Peptide, tumor necrosis factor (ligand) superfamily, member 18 Peptide, TNF superfamily member 18 Peptide, Tnfsf18 Peptide, TNFSF18 Peptide
- Background
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TNFSF18, also known as GITRL, belongs to the tumor necrosis factor(TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It is Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. Recombinant human TNFSF18 protein was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: TNFSF-18 protein, AITRL protein, hGITRL protein, TNFSF-18, GITRL protein, TNFSF 18, TNFSF18, TL6 protein, Tumor necrosis factor (ligand) superfamily member 18 protein, TNFSF 18 protein - Molecular Weight
- 14.6 kDa (129 AA)
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