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Ataxin 2-Binding Protein 1 (A2BP1) (Middle Region) Peptide

A2BP1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972682
  • Target See all A2BP1 products
    A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-A2BP1 antibody (Catalog #: ARP58203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
    Synonyms
    A2BP1 Peptide, fox1 Peptide, a2bp1 Peptide, zgc:103635 Peptide, 2BP1 Peptide, FOX-1 Peptide, FOX1 Peptide, HRNBP1 Peptide, A2bp Peptide, A2bp1 Peptide, Hrnbp1 Peptide, fox-1 Peptide, RNA binding protein, fox-1 homolog 1 Peptide, RNA binding fox-1 homolog 1 Peptide, multicopper ferroxidase Peptide, RNA binding protein, fox-1 homolog (C. elegans) 1 Peptide, RBFOX1 Peptide, rbfox1 Peptide, FOX1 Peptide, Rbfox1 Peptide
    Background
    Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Four alternatively spliced transcript variants have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

    Alias Symbols: FOX1, HRNBP1, 2BP1, A2BP1, FOX-1

    Protein Interaction Partner: ATN1,ATXN1,ATXN2,BAT2,CELF3,DMRTB1,DVL2,GCA,HNRNPF,HSFX1,KIFAP3,LZTS2,MAGED1,NOC2L,NUMBL,PCBP4,PSMF1,QKI,RBM24,RBM9,RHOXF2,TNIP1

    Protein Size: 395
    Molecular Weight
    42 kDa
    Gene ID
    54715
    NCBI Accession
    NM_145893, NP_665900
    UniProt
    Q9NWB1
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