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Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4) Peptide

ACCN4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN972804
  • Target See all ACCN4 products
    ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ACCN4 antibody (Catalog #: ARP35536_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ACCN4 (Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4))
    Synonyms
    ACCN4 Peptide, BNAC4 Peptide, Accn4 Peptide, Spasic Peptide, acid sensing ion channel subunit family member 4 S homeolog Peptide, acid sensing ion channel subunit family member 4 Peptide, acid-sensing (proton-gated) ion channel family member 4 Peptide, asic4.S Peptide, ASIC4 Peptide, Asic4 Peptide
    Background
    ACCN4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. ACCN4 is predominantly expressed in the pituitary gland, and might be a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder.

    Alias Symbols: ACCN4, BNAC4

    Protein Size: 417
    Molecular Weight
    46 kDa
    Gene ID
    55515
    NCBI Accession
    NM_182847
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