Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Peptide
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- Target See all ACSL5 products
- ACSL5 (Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACSL5 antibody (Catalog #: ARP47232_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACSL5 (Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5))
- Synonyms
- ACSL5 Peptide, acs2 Peptide, acs5 Peptide, facl5 Peptide, ACS2 Peptide, ACS5 Peptide, FACL5 Peptide, 1700030F05Rik Peptide, Facl5 Peptide, Acs5 Peptide, zgc:92083 Peptide, acyl-CoA synthetase long chain family member 5 Peptide, acyl-CoA synthetase long-chain family member 5 Peptide, ACSL5 Peptide, acsl5 Peptide, Acsl5 Peptide
- Background
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ASCL5 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: ACS2, ACS5, FACL5
Protein Size: 683 - Molecular Weight
- 76 kDa
- Gene ID
- 51703
- NCBI Accession
- NM_203379, NP_976313
- UniProt
- Q9ULC5
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