Alpha Centractin (ACTR1A) (Middle Region) Peptide
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- Target See all ACTR1A products
- ACTR1A (Alpha Centractin (ACTR1A))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACTR1A antibody (Catalog #: ARP58414_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACTR1A (Alpha Centractin (ACTR1A))
- Synonyms
- ARP1 Peptide, CTRN1 Peptide, Arp1 Peptide, alpha-Arp1 Peptide, arp1 Peptide, centractin Peptide, ctrn1 Peptide, ACTR1A Peptide, ARP1 actin related protein 1 homolog A Peptide, ARP1 actin-related protein 1A, centractin alpha Peptide, ARP1 actin-related protein 1 homolog A, centractin alpha Peptide, ARP1 actin related protein 1 homolog A L homeolog Peptide, alpha-centractin Peptide, actin-2 Peptide, ACTR1A Peptide, Actr1a Peptide, actr1a.L Peptide, actr1a Peptide, PTRG_02540 Peptide, PAAG_06972 Peptide, MCYG_01044 Peptide, VDBG_00685 Peptide, MGYG_00946 Peptide, DICPUDRAFT_88548 Peptide, PGTG_04034 Peptide, Tsp_06409 Peptide
- Background
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ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARP1, CTRN1
Protein Interaction Partner: ACTR1A,DCTN1,DCTN4,NUMA1,SPTBN1,SPTBN2,BICD2,DCTN4,NUMA1,SPTBN2
Protein Size: 376 - Molecular Weight
- 41 kDa
- Gene ID
- 10121
- NCBI Accession
- NM_005736, NP_005727
- UniProt
- P61163
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