Activin Receptor Type 1C (ACVR1C) (N-Term) Peptide
ACVR1C
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ACVR1C/ALK7 (ACVR1C) products
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACVR1C antibody (Catalog #: ARP52836_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- Synonyms
- ACVRLK7 Peptide, ALK7 Peptide, Alk-7 Peptide, C230097P10 Peptide, Alk7 Peptide, habrec1 Peptide, activin A receptor type 1C Peptide, activin A receptor, type IC Peptide, ACVR1C Peptide, Acvr1c Peptide
- Background
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ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
Alias Symbols: ACVRLK7, ALK7
Protein Interaction Partner: INHBB,TDGF1
Protein Size: 493 - Molecular Weight
- 55 kDa
- Gene ID
- 130399
- NCBI Accession
- NM_145259, NP_660302
- UniProt
- Q8NER5
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