Activin A Receptor Type II-Like 1 (ACVRL1) Peptide
ACVRL1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ACVRL1 products
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ACVRL1 antibody (Catalog #: ARP44199_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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Activin A Receptor Type II-Like 1 (ACVRL1) peptide
ACVRL1 Reactivity: Human Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- Synonyms
- ACVRL1 Peptide, vgb Peptide, alk1 Peptide, zehn1109 Peptide, hm:zehn1109 Peptide, ACVRLK1 Peptide, ALK-1 Peptide, ALK1 Peptide, HHT Peptide, HHT2 Peptide, ORW2 Peptide, SKR3 Peptide, TSR-I Peptide, R-3 Peptide, R3 Peptide, SETHKIR Peptide, AI115505 Peptide, AI427544 Peptide, Acvrlk1 Peptide, Alk1 Peptide, activin A receptor like type 1 Peptide, activin A receptor type II-like 1 Peptide, activin A receptor, type II-like 1 Peptide, ACVRL1 Peptide, acvrl1 Peptide, Acvrl1 Peptide
- Background
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ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Alias Symbols: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
Protein Interaction Partner: XIAP,ACVR2A,SNX6,TGFB1,TGFB3,TGFBR1,TGFBR2,TGFBRAP1,XIAP,SNX6,TGFB1
Protein Size: 503 - Molecular Weight
- 55 kDa
- Gene ID
- 94
- NCBI Accession
- NM_000020, NP_000011
- UniProt
- P37023
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