Amino-terminal Enhancer of Split (AES) (Middle Region) Peptide
AES
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AES products
- AES (Amino-terminal Enhancer of Split (AES))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AES antibody (Catalog #: ARP32323_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AES (Amino-terminal Enhancer of Split (AES))
- Synonyms
- AES-1 Peptide, AES-2 Peptide, ESP1 Peptide, GRG Peptide, GRG5 Peptide, TLE5 Peptide, AL024115 Peptide, Esp1 Peptide, Grg Peptide, Grg-5 Peptide, Grg5 Peptide, Tle5 Peptide, zgc:64216 Peptide, aes-1 Peptide, aes-2 Peptide, esp1 Peptide, grg Peptide, grg5 Peptide, tle5 Peptide, xgrg-5 Peptide, AES Peptide, amino-terminal enhancer of split Peptide, amino-terminal enhancer of split S homeolog Peptide, AES Peptide, Aes Peptide, aes Peptide, aes.S Peptide
- Background
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AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5
Protein Interaction Partner: AES,RELA,SIX1,SIX2,SIX3,SIX6,PTRH2,AR,ATN1,CCL7,GABARAP,GFI1B,GTF2E1,HMGB1,MED31,MSX1,POU2F1,PRDM1,PTRH2,RELA,RPL18A,SH3GL3,SIX1,SIX2,SIX3,SIX6,SNCAIP,AES,AR,GTF2E1,HMGB1,HNF1A,HNRNPAB,MED31,PTRH2,RELA,RUNX1,SH3GL3,SIX3,SIX6,STYXL1,TLE1,TLE3
Protein Size: 264 - Molecular Weight
- 29 kDa
- Gene ID
- 166
- NCBI Accession
- NM_198969, NP_945320
- UniProt
- Q14CJ1
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