Aldo-keto Reductase Family 1, Member C2 (AKR1C2) (N-Term) Peptide
AKR1C2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AKR1C2 products
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LEAVKLAIEA GFHHIDSAHV YNNEEQVGLA IRSKIADGSV KREDIFYTSK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AKR1C2 Antibody(ARP53506_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
- Synonyms
- AKR1C-pseudo Peptide, BABP Peptide, DD Peptide, DD2 Peptide, DDH2 Peptide, HAKRD Peptide, HBAB Peptide, MCDR2 Peptide, SRXY8 Peptide, Akr1c21 Peptide, aldo-keto reductase family 1 member C2 Peptide, aldo-keto reductase family 1, member C2 Peptide, AKR1C2 Peptide, Akr1c2 Peptide
- Background
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8
Protein Interaction Partner: AKR1C2
Protein Size: 323 - Molecular Weight
- 37 kDa
- Gene ID
- 1646
- NCBI Accession
- NM_205845, NP_995317
- UniProt
- P52895
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