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V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) Peptide

AKT2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973084
  • Target See all AKT2 products
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 9
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-AKT2 antibody (Catalog #: ARP30321_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
    Background
    AKT2 belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene encoding AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: PKBBETA, PRKBB, RAC-BETA, PKBB, HIHGHH

    Protein Interaction Partner: APPL1,CHUK,TCL1A,AKT1,AKT1S1,AKT2,APPL1,CHUK,ESR1,FOXO4,FSHR,GSK3B,HSP90AA1,MTCP1,PDPK1,RAB3D,SH3RF1,SLC2A4,TCL1A,TCL1B,TRIB3,TSC2,XIAP,APPL1,CHUK,GSK3B,MTCP1,PRKDC,SH3RF1,TCL1A,TCL1B

    Protein Size: 481
    Molecular Weight
    56 kDa
    Gene ID
    208
    NCBI Accession
    NM_001626, NP_001617
    UniProt
    P31751
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