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alpha-Methylacyl-CoA Racemase (AMACR) (C-Term) Peptide

AMACR Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN973162
  • Target See all AMACR products
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    IFDGTDACVT PVLTFEEVVH HDHNKERGSF ITSEEQDVSP RPAPLLLNTP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-AMACR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
    Synonyms
    AMACR Peptide, DKFZp469O1232 Peptide, amacr Peptide, NCU04099.1 Peptide, MGC89832 Peptide, AMACRD Peptide, CBAS4 Peptide, RACE Peptide, RM Peptide, Macr1 Peptide, Da1-8 Peptide, Marc1 Peptide, alpha-methylacyl-CoA racemase Peptide, PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) Peptide, Alpha-methylacyl-CoA racemase Peptide, alpha-methylacyl-CoA racemase L homeolog Peptide, AMACR Peptide, mcr Peptide, BPSL0064 Peptide, Maqu_2037 Peptide, UREG_03852 Peptide, MCYG_01809 Peptide, amacr Peptide, amacr.L Peptide, MGYG_04259 Peptide, NCU04099 Peptide, Amacr Peptide
    Background
    This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

    Alias Symbols: CBAS4, RACE, RM, AMACRD

    Protein Size: 382
    Molecular Weight
    42 kDa
    Gene ID
    23600
    NCBI Accession
    NM_014324, NP_055139
    UniProt
    Q9UHK6
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