Autophagy related 4B Cysteine Peptidase (ATG4B) Peptide
ATG4B
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all ATG4B products
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-APG4B antibody (Catalog #: ARP34434_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
- Synonyms
- apg4b Peptide, APG4B Peptide, AUTL1 Peptide, 2510009N07Rik Peptide, AW048066 Peptide, Apg4b Peptide, Atg4bl Peptide, Autl1 Peptide, Aut2b2 Peptide, autophagy related 4B cysteine peptidase Peptide, autophagy-related 4b Peptide, Peptidase family C54 protein Peptide, cysteine protease ATG4B Peptide, ATG4 autophagy related 4 homolog B (S. cerevisiae) Peptide, autophagy related 4B, cysteine peptidase Peptide, autophagy related 4B, cysteine peptidase L homeolog Peptide, ATG4B Peptide, Atg4b Peptide, AT3G59950 Peptide, Tsp_08582 Peptide, Tsp_11599 Peptide, atg4b Peptide, atg4b.L Peptide
- Background
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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: APG4B, AUTL1
Protein Interaction Partner: GABARAP,GABARAPL2,MAP1LC3B,C14orf139,FBXW11,GABARAP,GABARAPL2,MAP1LC3B
Protein Size: 393 - Molecular Weight
- 44 kDa
- Gene ID
- 23192
- NCBI Accession
- NM_013325, NP_037457
- UniProt
- Q9Y4P1
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