ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. The protein may function as a transcriptional regulator and play a role in hematopoiesis.
Alias Symbols: ASH2, ASH2L1, ASH2L2, Bre2
Protein Interaction Partner: DPY30,MEN1,MLL,MLL2,SMAD9,SMURF1,SMURF2,TGFBR1,UNC119,ASH2L,CHD8,CXXC1,DPY30,HCFC1,HCFC2,HIST3H3,KDM6A,MEN1,MLL,MLL3,MYB,PHF8,RBBP5,SETD1A,UNC119,WDR5,WDR82P1
Protein Size: 628