Autophagy related 4A Cysteine Peptidase (ATG4A) (N-Term) Peptide
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- Target See all ATG4A products
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATG4A antibody (Catalog #: ARP42689_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
- Synonyms
- apg4a Peptide, autl2 Peptide, F6E13.27 Peptide, APG4A Peptide, zgc:111958 Peptide, Aut2a Peptide, AUTL2 Peptide, AI627006 Peptide, AV169859 Peptide, Apg4a Peptide, Atg4al Peptide, Autl2 Peptide, Atg4a Peptide, autophagy related 4A cysteine peptidase L homeolog Peptide, autophagy related 4A cysteine peptidase Peptide, Peptidase family C54 protein Peptide, ATG4 autophagy related 4 homolog A (S. cerevisiae) Peptide, autophagy related 4A, cysteine peptidase Peptide, atg4a.L Peptide, ATG4A Peptide, AT2G44140 Peptide, atg4a Peptide, Atg4a Peptide
- Background
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Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Alias Symbols: APG4A, AUTL2
Protein Interaction Partner: GABARAPL2
Protein Size: 398 - Molecular Weight
- 45 kDa
- Gene ID
- 115201
- NCBI Accession
- NM_052936, NP_443168
- UniProt
- Q8WYN0
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