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ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2) (Middle Region) Peptide

ATP6V1B2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973633
  • Target See all ATP6V1B2 products
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ATP6V1B2 antibody (Catalog #: ARP56329_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))
    Synonyms
    Atp6b1b2 Peptide, Atp6b2 Peptide, Vatb Peptide, vha55 Peptide, VATB Peptide, ATP6B1B2 Peptide, ATP6B2 Peptide, HO57 Peptide, VPP3 Peptide, Vma2 Peptide, atp6v1bb Peptide, fj51e01 Peptide, vatB2 Peptide, wu:fj51e01 Peptide, zgc:109771 Peptide, AI194269 Peptide, AI790362 Peptide, R74844 Peptide, ATPase H+ transporting V1 subunit B2 Peptide, ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 S homeolog Peptide, ATPase, H+ transporting, lysosomal, V1 subunit B2 Peptide, ATPase, H+ transporting, lysosomal V1 subunit B2 Peptide, Atp6v1b2 Peptide, atp6v1b2.S Peptide, ATP6V1B2 Peptide, atp6v1b2 Peptide
    Background
    ATP6V1B2 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. ATP6V1B2 is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2

    Protein Size: 511
    Molecular Weight
    56 kDa
    Gene ID
    526
    NCBI Accession
    NM_001693, NP_001684
    UniProt
    P21281
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