beta 1,3-Galactosyltransferase-Like (B3GALTL) (Middle Region) Peptide
B3GALTL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all B3GALTL products
- B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-B3GALTL antibody (Catalog #: ARP49171_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- B3GALTL (beta 1,3-Galactosyltransferase-Like (B3GALTL))
- Synonyms
- B3GLCT Peptide, B3GTL Peptide, B3Glc-T Peptide, Gal-T Peptide, beta3Glc-T Peptide, Gm1057 Peptide, beta 3-glucosyltransferase Peptide, beta 3-glucosyltransferase L homeolog Peptide, beta-3-glucosyltransferase Peptide, B3GLCT Peptide, b3glct Peptide, b3glct.L Peptide, B3glct Peptide
- Background
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B3GALTL is the O-fucosyltransferase that transfers glucose toward fucose with a beta-1,3 linkage. B3GALTL specifically glucosylates O-linked fucosylglycan on TSP type-1 domains of proteins, thereby contributing to elongation of O-fucosylglycan.B3GALTL is a beta-1,3-glucosyltransferase involved in the synthesis of the unusual O-linked disaccharide glucosyl-beta-1,3-fucose-O- found on the thrombospondin (see THBS1, MIM 188060) type-1 repeats (TSRs) of many biologically important proteins. Biosynthesis of glucosyl-beta-1,3-fucose-O- is initiated by protein O-fucosyltransferase-2 (POFUT2, MIM 610249), which attaches the fucosyl residue to a serine or threonine within the TSR. B3GALTL subsequently transfers the glucose onto TSR-fucose (Hess et al., 2008 [PubMed 18199743]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-270 DN999521.1 41-310 271-457 AB101481.1 161-347 458-467 DN999521.1 499-508 468-1217 AB101481.1 358-1107 1218-1279 DA290408.1 515-576 1280-1607 AB101481.1 1170-1497 1608-2495 AY190526.1 1498-2385 2496-3459 AY190526.1 2387-3350 3460-4071 AV728071.1 87-698 4072-4221 AA769548.1 1-150 c
Alias Symbols: B3GTL, B3Glc-T, Gal-T, beta3Glc-T, B3GLCT
Protein Size: 498 - Molecular Weight
- 56 kDa
- Gene ID
- 145173
- NCBI Accession
- NM_194318, NP_919299
- UniProt
- Q6Y288
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