BCL2-Associated Agonist of Cell Death (BAD) (C-Term) Peptide
BAD
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BAD products
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BAD antibody (Catalog #: ARP30325_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Synonyms
- bad Peptide, fa01b12 Peptide, wu:fa01b12 Peptide, wu:fa96d04 Peptide, BAD Peptide, BBC2 Peptide, BCL2L8 Peptide, AI325008 Peptide, Bbc2 Peptide, BCL2-associated agonist of cell death b Peptide, BCL2 associated agonist of cell death Peptide, BCL2-associated agonist of cell death Peptide, badb Peptide, BAD Peptide, Bad Peptide
- Background
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BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Alias Symbols: BBC2, BCL2L8
Protein Interaction Partner: BCL2,BCL2,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,AKT1,BCL2,BCL2A1,BCL2L1,BCL2L10,BCL2L2,EWSR1,HRK,MAP2K5,MAPK8,MCL1,PAK1,PAK7,PIM1,PIM2,PIM3,PPP1CA,PPP3CA,PRKACA,RAF1,RPS6KA1,RPS6KA2,RPS6KA3,RPS6KA5,S100A10,SFN,SNCA,WASF1,YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,AKT1,BCL2,BCL2A1,BCL2L1,BCL2L1,BCL2L2,EWSR1,MCL1,PIM2,PRKACA,PRKCI,RPS6KA1,RPS6KA5,S100A10,SFN,SNCA,YWHAB,YWHAE,YWHAH,YWHAQ,YWHAZ
Protein Size: 168 - Molecular Weight
- 18 kDa
- Gene ID
- 572
- NCBI Accession
- NM_004322, NP_004313
- UniProt
- Q92934
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