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BMI1 Polycomb Ring Finger Oncogene (BMI1) (Middle Region) Peptide

BMI1 Reactivity: Human, Mouse Host: Synthetic BP, WB
Catalog No. ABIN973837
  • Target See all BMI1 products
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Protein Region
    Middle Region
    Origin
    Human, Mouse
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MDIPNTFQID VMYEEEPLKD YYTLMDIAYI YTWRRNGPLP LKYRVRPTCK
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-Bmi1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
    Synonyms
    FLVI2/BMI1 Peptide, PCGF4 Peptide, RNF51 Peptide, AW546694 Peptide, Bmi-1 Peptide, Pcgf4 Peptide, bmi1 Peptide, pcgf4 Peptide, psc1 Peptide, wu:fb17g03 Peptide, wu:fd18f06 Peptide, BMI-1 Peptide, pcgf4b Peptide, bmi-1 Peptide, bmi1-a Peptide, bmi1-b Peptide, bmi1b Peptide, rnf51 Peptide, xbmi-1 Peptide, BMI1 proto-oncogene, polycomb ring finger Peptide, BMI1 polycomb ring finger oncogene Peptide, Bmi1 polycomb ring finger oncogene Peptide, bmi1 polycomb ring finger oncogene 1a Peptide, bmi1 polycomb ring finger oncogene 1b Peptide, BMI1 proto-oncogene, polycomb ring finger L homeolog Peptide, BMI1 Peptide, LOC100230513 Peptide, Bmi1 Peptide, bmi1a Peptide, bmi1b Peptide, bmi1.L Peptide
    Background
    Bmi1 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

    Alias Symbols: AW546694, Bmi-1, Pcgf4

    Protein Interaction Partner: Phc2,Rnf2,CBX4,CBX8,Cbx2,Dmap1,Dnmt3b,HSPA4,Kdm2b,PHC1,PHC2,PHC3,Phc1,Phc3,RING1,Rnf2,SCMH1,SMARCA5,Slc11a1

    Protein Size: 324
    Molecular Weight
    37 kDa
    Gene ID
    12151
    NCBI Accession
    NM_007552, NP_031578
    UniProt
    P25916
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