BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (Middle Region) Peptide
BNIP3L
Reactivity: Mouse
Host: Synthetic
BP, WB
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- Target See all BNIP3L/NIX (BNIP3L) products
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
- Protein Region
- Middle Region
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Bnip3l Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
- Synonyms
- BNIP3a Peptide, NIX Peptide, NIP3 Peptide, Nix Peptide, Nip3 Peptide, C86132 Peptide, D14Ertd719e Peptide, Nip3L Peptide, bnip3l Peptide, nip3 Peptide, zgc:110478 Peptide, bnip3l2 Peptide, wu:fb52b03 Peptide, wu:fc02h04 Peptide, BCL2 interacting protein 3 like Peptide, BCL2 interacting protein 3 Peptide, BCL2/adenovirus E1B interacting protein 3 Peptide, BCL2/adenovirus E1B interacting protein 3-like Peptide, BCL2/adenovirus E1B interacting protein 3-like b Peptide, BCL2/adenovirus E1B interacting protein 3-like a Peptide, BNIP3L Peptide, BNIP3 Peptide, Bnip3l Peptide, Bnip3 Peptide, bnip3lb Peptide, bnip3la Peptide
- Background
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Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
Alias Symbols: C86132, D14Ertd719e, Nip3L, Nix
Protein Size: 218 - Molecular Weight
- 24 kDa
- Gene ID
- 12177
- NCBI Accession
- NM_009761, NP_033891
- UniProt
- Q9Z2F7
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