URI1, Prefoldin-Like Chaperone (URI1) (Middle Region) Peptide
URI1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all URI1 products
- URI1 (URI1, Prefoldin-Like Chaperone (URI1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-C19orf2 antibody (Catalog #: ARP50771_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- URI1 (URI1, Prefoldin-Like Chaperone (URI1))
- Synonyms
- c19orf2 Peptide, C19orf2 Peptide, NNX3 Peptide, PPP1R19 Peptide, RMP Peptide, URI Peptide, URI1 prefoldin-like chaperone L homeolog Peptide, URI1, prefoldin like chaperone Peptide, uri1.L Peptide, URI1 Peptide
- Background
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The function of the C19orf2 protein remains unknown.The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its binding to RPB5. The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5-binding region. This protein acts as a corepressor. It is suggested that it may require signaling processes for its function or that it negatively modulates genes in the chromatin structure. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FLJ10575, NNX3, RMP, URI, C19orf2, PPP1R19
Protein Interaction Partner: POLR2E,UXT,C19orf2,DMAP1,GTF2F2,POLR2E,STAP1,C19orf2,DMAP1,GPN1,POLR2E,RPAP2,RPAP3,RUVBL2,STAP1
Protein Size: 495 - Molecular Weight
- 55 kDa
- Gene ID
- 8725
- NCBI Accession
- NM_134447, NP_604431
- UniProt
- Q6NX55
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