Cysteinyl-tRNA Synthetase (CARS) Peptide
CARS
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all CARS products
- CARS (Cysteinyl-tRNA Synthetase (CARS))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARS antibody (Catalog #: ARP40297_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CARS (Cysteinyl-tRNA Synthetase (CARS))
- Synonyms
- sb:cb71 Peptide, CARS Peptide, BcDNA:LD21177 Peptide, CG8431 Peptide, CRS Peptide, CysRS Peptide, Dmel\\CG8431 Peptide, BA0089 Peptide, DDBDRAFT_0215191 Peptide, DDBDRAFT_0231320 Peptide, DDB_0215191 Peptide, DDB_0231320 Peptide, DDBDRAFT_0187313 Peptide, DDBDRAFT_0231318 Peptide, DDB_0187313 Peptide, DDB_0231318 Peptide, T16B12.16 Peptide, K15E6.3 Peptide, K15E6_3 Peptide, CARS1 Peptide, CYSRS Peptide, MGC:11246 Peptide, CA3 Peptide, cysteinyl-tRNA synthetase Peptide, Cysteinyl-tRNA synthetase Peptide, cysteine--tRNA ligase Peptide, cysteine-tRNA ligase Peptide, Cysteinyl-tRNA synthetase, class Ia family protein Peptide, cysteinyl-tRNA synthetase CysS Peptide, cysteinyl-tRNA synthetase S homeolog Peptide, CARS Peptide, cars Peptide, CysRS Peptide, cysS Peptide, APH_RS02395 Peptide, mcysS Peptide, SYCO ARATH Peptide, AT3G56300 Peptide, AT5G38830 Peptide, cars.S Peptide, Cars Peptide
- Background
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CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CARS1, CYSRS, MGC:11246
Protein Interaction Partner: EEF1G,EEF1G,PACSIN1,PACSIN2,PACSIN3,PSTPIP1
Protein Size: 738 - Molecular Weight
- 81 kDa
- Gene ID
- 833
- NCBI Accession
- NM_001014438, NP_001014438
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