Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3) Peptide
CBFA2T3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CBFA2T3 products
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CBFA2T3 antibody (Catalog #: ARP33993_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))
- Synonyms
- A630044F12Rik Peptide, AI465270 Peptide, AW229127 Peptide, Cbfa2t3h Peptide, ETO-2 Peptide, Eto2 Peptide, MTGR2 Peptide, MTG16a Peptide, MTG16b Peptide, ETO2 Peptide, MTG16 Peptide, ZMYND4 Peptide, core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) Peptide, CBFA2/RUNX1 translocation partner 3 Peptide, Cbfa2t3 Peptide, CBFA2T3 Peptide
- Background
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The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Alias Symbols: ETO2, MTG16, MTGR2, ZMYND4
Protein Interaction Partner: CBFA2T2,CBFA2T3,HDAC1,HDAC3,PRKAR2A,RUNX1,RUNX1T1,CBFA2T2,HDAC1,HDAC2,HDAC3,HDAC6,HDAC8,LDB1,NCOR1,PRKAR2A,RUNX1T1,TAL1,TCF3
Protein Size: 567 - Molecular Weight
- 62 kDa
- Gene ID
- 863
- NCBI Accession
- NM_175931, NP_787127
- UniProt
- O75082
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