Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD40 (CD40) Peptide

CD40 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN974676
  • Target See all CD40 products
    CD40
    Origin
    Human
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CD40 antibody (Catalog #: ARP41929_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CD40
    Synonyms
    Bp50 Peptide, CDW40 Peptide, TNFRSF5 Peptide, p50 Peptide, AI326936 Peptide, GP39 Peptide, HIGM1 Peptide, IGM Peptide, IMD3 Peptide, T-BAM Peptide, TRAP Peptide, Tnfrsf5 Peptide, TNFSF5 Peptide, CD40 molecule Peptide, CD40 antigen Peptide, CD40 Peptide, Cd40 Peptide
    Background
    CD40 is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

    Alias Symbols: Bp50, CDW40, MGC9013, TNFRSF5, p50

    Protein Interaction Partner: TRAF2,TRAF3,TRAF3,BIRC2,BIRC3,CAV1,CBL,CD40LG,HSPA4,HSPA8,IL4R,JAK3,MAP3K8,MS4A1,NSMAF,PIK3R1,RIPK2,TDP2,TRAF1,TRAF2,TRAF3,TRAF3IP2,TRAF5,TRAF6,XRCC5,XRCC6,CALR,DDX3X,ERP44,FBL,MS4A1,NCOA6,POLR2H,RFC5,RIPK2,RNF219,SGK1,SLC30A7,SLC39A7,SUMO1,TDP2,TRAF2,TRAF3,TRAF3IP2,TRAF5,TRAF6,TXN,UGGT1,USP15,XRCC5,XRCC6

    Protein Size: 277
    Molecular Weight
    30 kDa
    Gene ID
    958
    NCBI Accession
    NM_001250, NP_001241
    UniProt
    P25942
You are here:
Support