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Chromodomain Protein, Y-Like (CDYL) (N-Term) Peptide

CDYL Reactivity: Human Host: Synthetic BP, WB, ICC
Catalog No. ABIN974805
  • Target See all CDYL products
    CDYL (Chromodomain Protein, Y-Like (CDYL))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CDYL antibody (Catalog #: ARP49096_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CDYL (Chromodomain Protein, Y-Like (CDYL))
    Synonyms
    AI325931 Peptide, CDYL1 Peptide, chromodomain Y like Peptide, chromodomain protein, Y chromosome-like Peptide, chromodomain Y-like Peptide, CDYL Peptide, Cdyl Peptide
    Background
    CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.

    Alias Symbols: CDYL1, DKFZP586C1622, MGC131936

    Protein Interaction Partner: HDAC1,HDAC2,HTRA1,HDAC1,HDAC2

    Protein Size: 544
    Molecular Weight
    60 kDa
    Gene ID
    9425
    NCBI Accession
    NM_004824, NP_004815
    UniProt
    Q9Y232
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