Centromere Protein A (CENPA) Peptide
CENPA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CENPA products
- CENPA (Centromere Protein A (CENPA))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CENPA antibody (Catalog #: ARP46041_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CENPA (Centromere Protein A (CENPA))
- Synonyms
- CENP-A Peptide, CenH3 Peptide, Cenp-A Peptide, cenpx Peptide, cenp-a Peptide, sim2 Peptide, Cenp-a Peptide, RGD1563607 Peptide, CENPA Peptide, centromere protein A Peptide, centromere protein-A Peptide, centromeric histone-3 like protein Peptide, centromere-specific histone H3 CENP-A Peptide, cenp-A Peptide, centromere protein A L homeolog Peptide, histone H3-like centromeric protein A Peptide, CENPA Peptide, Cenpa Peptide, CENP-A Peptide, cenpa Peptide, cenp-A Peptide, cnp1 Peptide, HAN_3g422 Peptide, Cenp-a Peptide, cenpa.L Peptide, CMU_016480 Peptide
- Background
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Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA is a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CenH3, CENP-A
Protein Interaction Partner: DIAPH1,DIAPH2,AURKB,DIAPH1,DIAPH2,HIST1H3C,HIST1H4F,PARP1,PARP2,HIST1H3C,PARP1
Protein Size: 140 - Molecular Weight
- 16 kDa
- Gene ID
- 1058
- NCBI Accession
- NM_001809, NP_001800
- UniProt
- P49450
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