Centromere Protein H (CENPH) Peptide
CENPH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CENPH products
- CENPH (Centromere Protein H (CENPH))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CENPH antibody (Catalog #: ARP58266_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CENPH (Centromere Protein H (CENPH))
- Synonyms
- 1700021I11Rik Peptide, 2410018A12Rik Peptide, 2610042E16Rik Peptide, 2810046K12Rik Peptide, AU044255 Peptide, CENP-H Peptide, ENP Peptide, si:dkey-186m8.3 Peptide, cenp-h Peptide, centromere protein H Peptide, centromere protein H pseudogene Peptide, CENPH Peptide, Cenph Peptide, cenph Peptide, LOC100356112 Peptide, LOC101788801 Peptide
- Background
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Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NNF1, PMF1
Protein Interaction Partner: CENPH,KIF2C,CENPH,KIF2C,PMVK
Protein Size: 247 - Molecular Weight
- 27 kDa
- Gene ID
- 64946
- NCBI Accession
- NM_022909, NP_075060
- UniProt
- Q9H3R5
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