Coatomer Protein Complex, Subunit beta 1 (COPB1) Peptide
COPB1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all COPB1 products
- COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COPB1 antibody (Catalog #: ARP52371_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
- Synonyms
- id:ibd5034 Peptide, wu:fc66c05 Peptide, zgc:92482 Peptide, COPB1 Peptide, DKFZp459K154 Peptide, COPB Peptide, 2610019B04Rik Peptide, Rack2 Peptide, Beta-COP Peptide, coatomer protein complex, subunit beta 1 Peptide, coatomer protein complex subunit beta 1 L homeolog Peptide, coatomer protein complex subunit beta 1 Peptide, copb1 Peptide, copb1.L Peptide, COPB1 Peptide, Copb1 Peptide
- Background
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The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Alias Symbols: COPB, DKFZp761K102, FLJ10341
Protein Interaction Partner: ADAM19,ARCN1,nef,ADAM19,ARCN1,ARF1,COPE,COPG,COPG2,HLA-G,KCNK3,KDELR1,PDGFRB,PRKCE,RGS2,RGS4,RHOQ,TAPBP,TRIM37,UBQLN4,ADAM19,ARCN1,ARF1,COPA,COPB2,COPE,COPG,COPG2,HLA-A,HLA-G,KCNK3,KDELR1,PMS2,TAP1,TAPBP,TRIM37
Protein Size: 953 - Molecular Weight
- 107 kDa
- Gene ID
- 1315
- NCBI Accession
- NM_016451, NP_057535
- UniProt
- P53618
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