Mediator Complex Subunit 17 (MED17) Peptide
MED17
Reactivity: Human
Host: Synthetic
BP, WB, ChIP, IHC
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- Target See all MED17 products
- MED17 (Mediator Complex Subunit 17 (MED17))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CRSP6 antibody (Catalog #: ARP34192_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MED17 (Mediator Complex Subunit 17 (MED17))
- Synonyms
- crsp6 Peptide, CRSP6 Peptide, CRSP77 Peptide, DRIP80 Peptide, TRAP80 Peptide, 77kDa Peptide, C330002H14Rik Peptide, Crsp6 Peptide, Trap80 Peptide, mediator of RNA polymerase II transcription subunit 17 Peptide, mediator complex subunit 17 Peptide, mediator complex subunit 17 L homeolog Peptide, AOR_1_2446154 Peptide, VDBG_01663 Peptide, med17 Peptide, med17.L Peptide, MED17 Peptide, Med17 Peptide
- Background
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
Protein Interaction Partner: MED19,MED22,MED30,MED19,MED22,MED30,MED8,TP53,USP49,BARD1,BRCA1,BRD4,CDK8,ESR1,ESR2,GATA1,GPN1,HNF4A,MED1,MED10,MED18,MED19,MED25,MED26,MED28,MED29,MED30,MED9,PPARGC1A,RPAP2,SMARCA4,TP53
Protein Size: 651 - Molecular Weight
- 73 kDa
- Gene ID
- 9440
- NCBI Accession
- NM_004268, NP_004259
- UniProt
- Q9NVC6
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