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CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) Peptide

CTCFL Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975412
  • Target See all CTCFL products
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CTCFL antibody (Catalog #: ARP36128_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
    Synonyms
    BORIS Peptide, CT27 Peptide, CTCF-T Peptide, HMGB1L1 Peptide, dJ579F20.2 Peptide, CTCFL Peptide, Boris Peptide, OTTMUSG00000016680 Peptide, CCCTC-binding factor like Peptide, CCCTC-binding factor (zinc finger protein)-like Peptide, CTCFL Peptide, Ctcfl Peptide
    Background
    CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and CTCFL are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: BORIS, CTCF-T, MGC163358, dJ579F20.2, CT27, HMGB1L1

    Protein Interaction Partner: BRCA1

    Protein Size: 663
    Molecular Weight
    76 kDa
    Gene ID
    140690
    NCBI Accession
    NM_080618, NP_542185
    UniProt
    Q8NI51
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