Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1) Peptide
DEAF1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DEAF1 products
- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DEAF1 antibody (Catalog #: ARP39467_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DEAF1 (Deformed Epidermal Autoregulatory Factor 1 (Drosophila) (DEAF1))
- Synonyms
- AU042387 Peptide, C230009B13Rik Peptide, NUDR Peptide, SPN Peptide, ZMYND5 Peptide, MYND5 Peptide, spn Peptide, DEAF1 Peptide, nudr Peptide, zmynd5 Peptide, CG8567 Peptide, DEAF-1 Peptide, Deaf-1 Peptide, Dmel\\CG8567 Peptide, deaf1 Peptide, l(3)76BDv Peptide, deformed epidermal autoregulatory factor 1 (Drosophila) Peptide, DEAF1, transcription factor Peptide, DEAF1 transcription factor Peptide, deformed epidermal autoregulatory factor 1 homolog Peptide, Deformed epidermal autoregulatory factor-1 Peptide, Deaf1 Peptide, DEAF1 Peptide, LOC509260 Peptide, deaf1 Peptide, deaf-1 Peptide
- Background
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DEAF1 down-regulates transcription of those genes by binding to sequence with multiple copies of TTC[CG]G present in their own promoter and that of the HNRPA2B1 gene. DEAF1 binds to the retinoic acid response element (RARE) AGGGTTCACCGAAAGTTCA. DEAF1 activates the proenkephalin gene independently of promoter binding, probably through protein-protein interaction. When secreted, behaves as an inhibitor of cell proliferation, by arresting cells in the G0 or G1 phase.
Alias Symbols: NUDR, SPN, ZMYND5
Protein Interaction Partner: DEAF1,ASCC2,INTS1,ASCC2,LMO4
Protein Size: 565 - Molecular Weight
- 59 kDa
- Gene ID
- 10522
- NCBI Accession
- NM_021008, NP_066288
- UniProt
- O75398
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