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Disrupted in Schizophrenia 1 (DISC1) Peptide

DISC1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN975803
  • Target See all DISC1 products
    DISC1 (Disrupted in Schizophrenia 1 (DISC1))
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-DOT1L antibody (Catalog #: ARP47938_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DISC1 (Disrupted in Schizophrenia 1 (DISC1))
    Synonyms
    DISC1 Peptide, C1orf136 Peptide, SCZD9 Peptide, disrupted in schizophrenia 1 Peptide, disrupted in schizophrenia 1 protein Peptide, disc1 Peptide, DISC1 Peptide, LOC100580606 Peptide, Disc1 Peptide
    Background
    DOT1L is a histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones.

    Alias Symbols: DOT1, KIAA1814, KMT4, SCZD9, C1orf136

    Protein Interaction Partner: ACTN2,ANKHD1,ATF4,ATF5,ATF7IP,EIF3H,ITSN1,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,TRAF3IP1,ACTN2,ATF4,ATF5,ATF7IP,CCDC141,CIT,DISC1,EIF3H,FEZ1,ITSN1,KCNQ5,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,SYNE1,TRAF3IP1,YWHAG,ACTN2,ATF4,ATF4,ATF5,ATF7IP,CCDC141,CEP290,CEP63,CIT,COL4A1,EIF3A,EIF3H,EPB49,FEZ1,GOLGA2,IMMT,ITSN1,KALRN,KATNAL1,KCNQ5,KIAA1377,MAP1A,MGAT3,MYO1A,NDE1,NDEL1,PPFIA4,RANBP9,RASSF7,SMARCE1,SPTAN1,SPTBN4,SYNE1,TRAF3IP1,YWHAG

    Protein Size: 1537
    Molecular Weight
    165 kDa
    Gene ID
    27185
    NCBI Accession
    NM_032482, NP_115871
    UniProt
    Q8TEK3
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