Disrupted in Schizophrenia 1 (DISC1) Peptide
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- Target See all DISC1 products
- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DOT1L antibody (Catalog #: ARP47938_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DISC1 (Disrupted in Schizophrenia 1 (DISC1))
- Synonyms
- DISC1 Peptide, C1orf136 Peptide, SCZD9 Peptide, disrupted in schizophrenia 1 Peptide, disrupted in schizophrenia 1 protein Peptide, disc1 Peptide, DISC1 Peptide, LOC100580606 Peptide, Disc1 Peptide
- Background
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DOT1L is a histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones.
Alias Symbols: DOT1, KIAA1814, KMT4, SCZD9, C1orf136
Protein Interaction Partner: ACTN2,ANKHD1,ATF4,ATF5,ATF7IP,EIF3H,ITSN1,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,TRAF3IP1,ACTN2,ATF4,ATF5,ATF7IP,CCDC141,CIT,DISC1,EIF3H,FEZ1,ITSN1,KCNQ5,MAP1A,NDEL1,PCNT,RANBP9,SPTBN4,SYNE1,TRAF3IP1,YWHAG,ACTN2,ATF4,ATF4,ATF5,ATF7IP,CCDC141,CEP290,CEP63,CIT,COL4A1,EIF3A,EIF3H,EPB49,FEZ1,GOLGA2,IMMT,ITSN1,KALRN,KATNAL1,KCNQ5,KIAA1377,MAP1A,MGAT3,MYO1A,NDE1,NDEL1,PPFIA4,RANBP9,RASSF7,SMARCE1,SPTAN1,SPTBN4,SYNE1,TRAF3IP1,YWHAG
Protein Size: 1537 - Molecular Weight
- 165 kDa
- Gene ID
- 27185
- NCBI Accession
- NM_032482, NP_115871
- UniProt
- Q8TEK3
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