DPH1 Homolog (DPH1) Peptide
DPH1
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all DPH1 products
- DPH1 (DPH1 Homolog (DPH1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DPH1 antibody (Catalog #: ARP51956_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DPH1 (DPH1 Homolog (DPH1))
- Synonyms
- DPH1 Peptide, DPH1-OVCA2 Peptide, dph1-ovca2 Peptide, dph2l Peptide, dph2l1 Peptide, ovca1 Peptide, DPH2L Peptide, DPH2L1 Peptide, OVCA1 Peptide, zgc:110702 Peptide, 2310011M22Rik Peptide, 4930488F09Rik Peptide, AW551873 Peptide, Dph2l1 Peptide, Ovca1 Peptide, RGD1562694 Peptide, diphthamide biosynthesis 1 Peptide, diphthamide biosynthesis protein 1 Peptide, diphthamide biosynthesis 1 L homeolog Peptide, 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 Peptide, DPH1 Peptide, NCU08503 Peptide, ATEG_01183 Peptide, LELG_00973 Peptide, HCAG_03806 Peptide, AOR_1_728014 Peptide, PTRG_05729 Peptide, CTRG_01524 Peptide, UREG_06411 Peptide, BDBG_05574 Peptide, MCYG_04396 Peptide, PITG_12187 Peptide, MGYG_02224 Peptide, LOC100284663 Peptide, dph1.L Peptide, dph1 Peptide, Dph1 Peptide, dph-1 Peptide
- Background
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Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]). Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-40 AF321876.1 1-40 41-1028 BC003099.1 3-990 1029-1410 BP417755.1 78-459 1411-2188 AK090530.1 1484-2261 2189-2200 AF321876.1 2189-2200
Alias Symbols: DPH2L, DPH2L1, FLJ33211, OVCA1
Protein Interaction Partner: HSPA5,RBM8A,HSPA5,RBM8A
Protein Size: 443 - Molecular Weight
- 49 kDa
- Gene ID
- 1801
- NCBI Accession
- NM_001383, NP_001374
- UniProt
- Q9BZG8
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