Diphthamide Biosynthesis Protein 2 (DPH2) Peptide
DPH2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DPH2 products
- DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DPH2 antibody (Catalog #: ARP51958_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DPH2 (Diphthamide Biosynthesis Protein 2 (DPH2))
- Synonyms
- DPH2L2 Peptide, 9130020C19Rik Peptide, AI467389 Peptide, Dph2l2 Peptide, id:ibd5058 Peptide, zgc:162269 Peptide, DPH2 homolog Peptide, DPH2 homolog (S. cerevisiae) Peptide, hypothetical protein Peptide, DPH2 Peptide, Dph2 Peptide, dph2 Peptide, CAALFM_C400690CA Peptide
- Background
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This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. This gene is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: DPH2L2
Protein Size: 489 - Molecular Weight
- 52 kDa
- Gene ID
- 1802
- NCBI Accession
- NM_001384, NP_001375
- UniProt
- Q9BQC3
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