DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24) Peptide
DNAJC24
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DNAJC24 products
- DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DPH4 antibody (Catalog #: ARP53399_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DNAJC24 (DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24))
- Synonyms
- DPH4 Peptide, JJJ3 Peptide, ZCSL3 Peptide, 1700030A21Rik Peptide, 2610027M02Rik Peptide, AV066965 Peptide, AW240712 Peptide, Dph4 Peptide, MmDjC7 Peptide, Zcsl3 Peptide, RGD1564710 Peptide, DnaJ heat shock protein family (Hsp40) member C24 Peptide, DNAJC24 Peptide, Dnajc24 Peptide
- Background
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Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2.Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-10 CD685768.1 19-28 11-652 AL833128.1 1-642 653-3000 AC108456.7 42515-44862
Alias Symbols: JJJ3, ZCSL3, DPH4
Protein Size: 149 - Molecular Weight
- 17 kDa
- Gene ID
- 120526
- NCBI Accession
- NM_181706, NP_859057
- UniProt
- Q6P3W2
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