Desmocollin 3 (DSC3) (N-Term) Peptide
DSC3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all Desmocollin 3 (DSC3) products
- Desmocollin 3 (DSC3)
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DSC3 antibody (Catalog #: ARP45195_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Desmocollin 3 (DSC3)
- Synonyms
- CDHF3 Peptide, DSC Peptide, DSC1 Peptide, DSC2 Peptide, DSC4 Peptide, HT-CP Peptide, 5430426I24Rik Peptide, MGC85083 Peptide, desmocollin 3 Peptide, desmocollin 3 S homeolog Peptide, DSC3 Peptide, Dsc3 Peptide, dsc3.S Peptide, dsc3 Peptide
- Background
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DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
Alias Symbols: CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP
Protein Interaction Partner: PKP3,PKP3,CTNNB1,JUP,PKP3,PKP4,CTNNB1,JUP,PKP3,PKP4
Protein Size: 896 - Molecular Weight
- 85 kDa
- Gene ID
- 1825
- NCBI Accession
- NM_001941, NP_001932
- UniProt
- Q14574
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